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VII ALBA Users' Meeting

3–4 Sept 2026
ALBA Synchrotron
Europe/Madrid timezone

Session

Life Sciences

4 Sept 2026, 11:00
ALBA Synchrotron

ALBA Synchrotron

Presentation materials

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  1. 25. Invited Speaker
    Elena Longo (Elettra Sincrotrone, Italy)
    04/09/2026, 11:00
    Oral contribution
  2. 108. Design and cryo-EM structures of protein cages based on helical fusion and machine learning
    Dr Roger Castells-Graells (Spanish National Cancer Research Centre (CNIO))
    04/09/2026, 11:30
    Oral contribution

    Self-assembling protein cages are versatile nanoscale architectures with broad applications in drug delivery, vaccine development, and structural biology. Historically, two main strategies have been used to construct such cages: genetic fusion of oligomeric domains connected by helical linkers, and computational interface design using either physics-based or machine learning-based methods....

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  3. 91. An integrated cloud-based platform for synchrotron X-ray phase contrast imaging data analysis and clinical data management
    Mariana Lourenço Seabra (University Pompeu Fabra)
    04/09/2026, 11:50
    Oral contribution

    Synchrotron-based X-ray phase-contrast imaging (X-PCI) enables non-destructive, high-resolution three-dimensional visualisation of soft-tissue microstructure at sub-micron scales, offering unique insights into tissue organisation that are inaccessible with conventional histology [1]. However, the analysis and clinical interpretation of synchrotron datasets in research and clinical contexts...

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  4. 48. Structural elucidation of a dehalogenase designed with REXzyme: an encoder-decoder model trained on enzymatic reactions
    Dr Ramiro Illanes Vicioso (Centre of Genomic Regulation)
    04/09/2026, 12:10
    Oral contribution

    Per- and polyfluoroalkyl substances (PFAS) belong to a family of more than 4000 compounds known as “forever chemicals”; the high stability of C–F bonds hinders their degradation, hence their extensive spread and presence in the environment. PFAS have been related to a broad spectrum of medical conditions such as hypothyroidism, decreased antibody levels in neonates, or endometrial...

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  5. 60. Multimodal Imaging of Silica Nanoparticle Distribution: Impact of Concentration and Cell Doubling Time
    Isabella Scarpa (ALBA Synchrotron)
    04/09/2026, 12:30
    Oral contribution

    Silica nanoparticles (SiNPs) have emerged as promising nanoplatforms for both the diagnosis and treatment of diseases. A comprehensive understanding of nanoparticle–cell interactions is essential for advancing nanomedicine, yet most studies rely on static observations and lack volumetric information under near-native conditions. Among the factors influencing cellular uptake, the formation of...

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  6. 27. Invited Speaker
    Tobias Weinert (PSI)
    04/09/2026, 12:50
    Oral contribution
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