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X AUSE Conference & V ALBA User's meeting

5–8 Sept 2022
ALBA Synchrotron
Europe/Madrid timezone

Session

ALBA A - 08/09/22 II

8 Sept 2022, 15:00
Maxwell Auditorium (ALBA Synchrotron)

Maxwell Auditorium

ALBA Synchrotron

Carrer de la Llum 2-26

Conveners

ALBA A - 08/09/22 II

  • Judith Juanhuix Gibert

Presentation materials

There are no materials yet.

  1. 101. High-sensitivity quantitative X-ray phase-contrast imaging for biomedical applications
    Prof. Julia Herzen (Biomedical Imaging Physics, School of Natural Sciences, Department of Physics & Munich Institute of Biomedical Engineering, Technical University of Munich)
    08/09/2022, 15:00
    Oral

    Phase-contrast X-ray imaging uses the refraction of X-rays to generate the contrast. It has been demonstrated to provide superior soft-tissue contrast in comparison to conventional attenuation-based X-ray imaging. However, quantitative imaging of biomedical soft tissue at high spatial resolution and high image quality still remains challenging. Some existing methods require assumptions on the...

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  2. 100. Applying soft X-ray tomography to support therapeutic development for Muscular Dystrophies
    Cecilia Jiménez Mallebreda (Neuromuscular Unit, Institut de Recerca Sant Joan de Déu. Department of Genetics, Microbiology and Statistics, University of Barcelona)
    08/09/2022, 15:30
    Oral

    Our aim was to apply high resolution and precision techniques to investigate the efficacy of gene editing to revert the cellular and biochemical phenotype of cells harbouring collagen VI mutations which give raise to a severe form of Muscular Dystrophy. Soft X-ray tomography can provide new structural and complementary results given that no sectioning is required, thus preserving the...

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  3. 9. The potential of synchrotron-based cryo-X-ray phase contrast imaging of myocardial biopsies
    Ms Kan Yan Chloe Li (UCL Institute of Cardiovascular Science, University College London, London, United Kingdom)
    08/09/2022, 16:00
    Oral

    Cardiomyopathies are serious heart muscle (myocardial) abnormalities which can lead to life-threatening complications such as heart failure, cardiac arrest, and sudden death. Myocardial biopsies obtained from surgical septal myectomies are essential for confirming diagnosis of cardiomyopathies. Owing to the recent advancements of synchrotron radiation-based X-ray phase contrast imaging (XPCI),...

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  4. 102. Chemical modulation of microtubule structure in neurodegenerative diseases
    María A. Oliva Blanco (CSIC-Centro de Investigaciones Biologicas Margarita Salas)
    08/09/2022, 16:30
    Oral

    Microtubules (MTs) are dynamic filaments involved in many essential cellular functions including those needed for cancer cell growth. Taxanes are MT stabilizing agents and the most successful antitumoral drugs targeting MTs. However, despite their mode of action is the stabilization (i.e., do not destroy the filament structure), they produce a paradoxical neurotoxic effect by inducing axon...

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