X AUSE Conference & V ALBA User's meeting

Session

ALBA A - 08/09/22 I

8 Sept 2022, 11:30

Maxwell Auditorium (ALBA Synchrotron)

Conveners

ALBA A - 08/09/22 I

• Olga Lopez (IQAC-CSIC)

99. Perspectives of Life Science at ALBA

Judith Juanhuix Gibert (ALBA Synchrotron)

08/09/2022, 11:30

Oral

The Life Sciences scientific program at the ALBA synchrotron has been well established for years, with several beamlines covering multiple techniques widely used in structural molecular and cellular biology. Still, as part of the future ALBA-II upgrade, the program is being further developed to offer new techniques. The existing beamlines are planned to undergo throughout upgrades in the...

123. Serial Crystallography ready for XALOC users: from SMX @ALBA to SFX @EuXFEL

Xavier Carpena Vilella (ALBA Synchrotron)

08/09/2022, 12:00

Oral

In the new Alphafold2 era, the interest of structural biologists on macromolecular dynamics has increased. Synchrotron Serial Crystallography (SSX) may still be not so known among crystallographers as single-crystal MX, however, the serial data collection of multiple non cryocooled microcrystals opens the door not only to projects including radiation sensitive targets (as metalloproteins) or...

124. What can the CryoEM Platform do for you?

Pablo Guerra Lahoz (IBMB-CSIC)

08/09/2022, 12:25

Oral

The new Cryo-electron Microscope Platform possess a specialized cryo-electron microscope for structural biology applications, equipped with an automated sample load system and a last generation direct electron detector Falcon IV. The platform will give access to state-of-the-art cryo-EM equipment for structure determination projects using the latest technology and methods.
This equipment will...

10. Application of |ρ| - based direct methods to the solution of anomalous scatterers substructures from SAD data of protein crystals

Jordi Rius (ICMAB-CSIC)

08/09/2022, 12:50

Oral

Owing to the importance of the SAD technique, |ρ|-based direct methods in the form of the recent SMAR (= SM,|ρ|) phasing algorithm incorporating the inner-pixel-preservation (ipp) procedure [Rius, J.& Torrelles, X. (2021) Acta Cryst A77, 489-493] have been adapted to the determination of anomalous scatterers substructures. Their applicability has been tested on a series of...

45. Peptide Amphiphilic-Based Supramolecular Structures Interaction with Liposomes

Ramon Pons (IQAC-CSIC), Dr Isabel Haro (IQAC-CSIC), Dr Maria José Gómara (IQAC-CSIC)

08/09/2022, 13:10

Oral

We have used SAXS to investigate the incorporation of several peptide amphiphiles to vesicles. These modified peptides have been shown to have amphiphilic properties. Vesicles have distinct SAXS features that provide information about the electronic density across the bilayer. We have adopted a multiple Gaussian description of the bilayers using several constrains to keep the number of fitting...