X AUSE Conference & V ALBA User's meeting

Session

XFEL II

7 Sept 2022, 11:30

Maxwell Auditorium (ALBA Synchrotron)

Conveners

XFEL II

• Chris Milne (European XFEL, Germany)

73. Opportunities in Non-equilibrium (Bio)chemistry via THz-driven Water Dynamics

Sergio Carbajo (UCLA and Stanford)

07/09/2022, 11:30

Keynote

Liquid water is the single most important medium in which highly consequential chemical and biological processes take place. Water is often equivocally regarded as a passive medium. Ranging from an isolated molecule to small clusters and up to bulk, water shows unique and ubiquitous behavior at different temperatures and environments. The main reason is the presence of a strong H-bond...

84. Mix-and-probe serial femtosecond crystallography enables the visualisation of an enzyme:substrate complex at room temperature

Albesa David (Instituto Biofisika (CSIC, UPV/EHU), Ikerbasque)

07/09/2022, 12:00

Oral

Understanding the basis of enzyme catalysis at the molecular level has been a fundamental goal of biochemistry and structural biology. The “recording” of an enzymatic reaction as it happens represents a significant challenge because many of the enzyme:substrate/transition-state/product complexes are transients, making them invisible to standard crystallographic techniques. X-ray free-electron...

89. Femtosecond-to-Millisecond Structural Biology using Synchrotrons and X-ray Lasers

Jörg Standfuss (Laboratory of Biomolecular Research, Paul Scherrer Institute, Switzerland)

07/09/2022, 12:20

Oral

Providing detailed experimental insights into how proteins change over time and to relate these structural changes to biological function remains one of the major challenges in structural biology. Next generation X-ray sources including diffraction-limited synchrotrons and X-ray Free Electron Lasers offer exciting new opportunities to study protein dynamics by time-resolved pump-probe...

108. Tracking phase transitions at extreme conditions of pressures and temperatures using high-energy lasers and XFELs

Marion Harmand (IMPMC, Institut de Minéralogie, Physique de la Matière Condensée et Cosmochimie Sorbonne Université – CNRS )

07/09/2022, 12:40

Plenary

Studying matter under extreme conditions is critically important for a wide range of science application including, for example planetary science, astrophysical high-velocity impacts as well as industrial applications. While laser compression is playing a major role in exploring phase diagrams at extreme condition of pressures and temperatures, the associated physical processes and phase...