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X AUSE Conference & V ALBA User's meeting

5–8 Sept 2022
ALBA Synchrotron
Europe/Madrid timezone

Session

AUSE A - 06/09/22 III

6 Sept 2022, 17:30
Maxwell Auditorium (ALBA Synchrotron)

Maxwell Auditorium

ALBA Synchrotron

Carrer de la Llum 2-26

Conveners

AUSE A - 06/09/22 III

  • Christina Kamma-Lorger (Scattering group, Australian Synchrotron – ANSTO)

Presentation materials

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  1. 18. Towards deciphering Catalytic Mechanisms by Time-Resolved Serial Femtosecond Crystallography at XFELs
    Alice Grieco (Dept. Crystallography & Structural Biology. Institute of Physical Chemistry Rocasolano, Spanish National Research Council (CSIC), Madrid, Spain)
    06/09/2022, 17:30
    Oral

    Time-resolved serial femtosecond crystallography (TR-SFX) is a revolutionary scientific-technical breakthrough that makes use of the highly-intense, ultra-short X-ray pulses produced at X-ray Free Electron Lasers (XFELs) to study structural dynamics of biological macromolecules in “real time” by using nano/microcrystals under nearly "native" conditions. In our group, we are interested in...

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  2. 68. Structural characterization, from synchrotron powder X-ray diffraction data of solid forms of Apremilast, a case of rich isostructural solvatomorphism
    Dr Cristina Puigjaner (Universitat de Barcelona)
    06/09/2022, 17:50
    Oral

    Active Pharmaceutical Ingredients (APIs) can exist in different crystalline forms,
    demanding a thorough investigation of their solid form landscape during drug discovery. Solvate formation is a common occurrence and in some cases, solvates can serve as intermediates in the production of the optimal form for further development. More challenging is to understand the reason for the formation of...

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