Hands-on workshop on Macromolecular Crystallography

Monday 23 Oct 2017, 09:00 → 16:30 UTC

Maxwell Auditorium (ALBA Synchrotron)

Bárbara Dr. Machado Calisto, Roeland Boer (ALBA Synchrotron)

This workshop will discuss the different protocols to optimize data collection of native or anomalous MX data with MXCuBE (which will soon be operational at XALOC), data processing with XDS and ab initio phasing with ARCIMBOLDO.

The workshop will also include a tutorial on the analysis of difficult cases provided by the assistants, a demo of new beamline capabilities such as in-situ crystal diffraction and a visit to ALBA.

Poster Poster_WorkshopMX.pdf

1 Welcome message

Speaker: Prof. Miguel A. G. Aranda (ALBA-CELLS) (ALBA-CELLS)

2 Macromolecular Crystallography at ALBA

3 Advanced data collection procedures with MXCuBE

ID29 MX beamline, ESRF, Grenoble, France

Speaker: Dr Daniele de Sanctis (ESRF)

4 Data quality in macromolecular crystallography

Speaker: Dr Kay Diederichs (Universität Konstanz) (Universität Konstanz, Konstanz, Germany)

11:00 Coffee break

5 Arcimboldo @ XALOC

Speaker: Prof. Isabel USÓN (SBU, IBMB-CSIC) (IBMB-CSIC)

6 Structural Insights on Regulation of Peptidoglycan Recycling and Antibiotics Resistance in P. aeruginosa

Speaker: Dr Juan Hermoso (Inst. Rocasolano-CSIC) (Instituto Rocasolano-CSIC, Madrid, Spain)

7 Striving Toward a Cure for Prostate Cancer using X-ray Crystallography

Speaker: Dr Eva Estébanez-Perpiñá (IBUB) (Dept. Biochemistry and Molecular Biomedicine, IBUB, Barcelona, Spain)

8 Round table

13:30 Lunch

9 Activities running in parallel in small groups

* Tutorial on XDS (Tesla Room, 2nd floor) * Demo of new beamline capabilities (XALOC control hutch) * Visit to ALBA