Integrative Structural Biology Symposium

14 Nov 2024, 08:30 → 15 Nov 2024, 18:00 Europe/Madrid

Parc Científic de Barcelona (14/11/2024) - ALBA Synchrotron (15/11/2024)

The Spanish Integrative Structural Biology Infrastructure Network (ISBIN) is pleased to announce the symposium on the integrative use of NMR, cryo-electron microscopy, synchrotron radiation techniques, and computation in the city of Barcelona and the site of the nearby ALBA Synchrotron Light facility the 14 and 15 November of 2024.

                                             

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Thursday, 14 November

Registration at Parc Científic de Barcelona (PCB)

1 Welcome

2 Integrating NMR with cryo-EM to tackle dynamic protein complexes

Speaker: Charalampos Kalodimos (St Jude Children's Research Hospital, USA)

3 "Lifting" the curtain on the molecular architecture of extracellular matrix using cryo-electron tomography

Speaker: Florian Schur (Institute of Science and Technology, Austria)

11:00 Coffee Break

4 A Structural Perspective of the Pathological Threshold in Huntington’s Disease

Speaker: Pau Bernadó, (Centre de Biochimie Structurale, France)

5 Deciphering chromatin organization and key DNA repair processes in the radiation resistant bacterium, Deinococcus radiodurans, using an integrated structural and cell biology approach

Speaker: Joanna Timmins (Institute of Biologie Structurale, France)

6 Beyond Structures: Deciphering the Regulatory Interplay between Cell-Wall Degrading Machineries and Bacterial Cell Division

Speaker: Juan Hermoso (Institute of Physical Chemistry Blas Cabrera, Spain)

13:00 Lunch

7 Integrated Structural Biology Studies, focusing on RNA

Speaker: Harald Schwalbe (University of Frankfurt, Germany)

8 Invited talk

Speaker: Israel S. Fernández (Biofisika Institute, Spain)

9 XFEL- and synchrotron-based serial crystallography studies of the membrane-bound proton pump cytochrome c oxidase

Speaker: Gisela Brändén (University of Gothenburg, Sweden)

16:00 Coffee Break

10 Cryogenic probes to enhance Solid-state NMR signal detection in Integrative Structural Biology: Applications to Protein Assemblies

Speaker: Miguel Mompeán (Institute of Physical Chemistry Blas Cabrera, Spain)

11 SymProFold: Structural prediction of symmetrical biological assemblies

Speaker: Tea Pavkov-Keller (University of Graz, Austria)

Friday, 15 November

08:30 Bus departure from PCB and hotel to ALBA synchrotron

12 Harnessing Synergy: NMR and Synchrotron Radiation Illuminate the DNA Damage Response

Speaker: Irene Díaz (University of Sevilla, Spain)

13 Shedding light onto the Protein Universe at unprecedented scales

Speaker: Joanna Pereira (Biozentrum Basel, Switzerland)

14 Unveiling the Molecular Bases of RNA Virus Replication Using Integrative Structural Biology

Speaker: Núria Verdaguer (Institute of Molecular Biology of Barcelona, Spain)

11:00 Coffee Break

15 Cryo Electron Microscopy and the new image processing methods to handle conformational and compositional heterogeneity

Speaker: José Maria Carazo (National Centre for Biotechnolgy, Spain)

16 The T-REXX endstation on beamline P14 at PETRA III: working towards improving the accessibility of time-resolved macromolecular crystallography

The T-REXX endstation on beamline P14 at PETRA III: working towards improving the accessibility of time-resolved macromolecular crystallography

Speaker: Arwen Pearson (University of Hamburg, Germany)

17 XAIRA beamline at ALBA: Advancing macromolecular crystallography with low background diffraction and micron-sized beam

Speaker: Damià Garriga (ALBA Synchrotron Light Souce, Spain)

18 Announcements

19 Closing Remarks

13:30 Lunch

20 Visit to ALBA beamlines

Bus departure to Barcelona: Bus departure to Barcelona-Plaça Espanya